It is located in the center of the city. It was built in 1900 for the wealthy merchant Jovan Popić, by Italian builders who stayed in Niš after the construction of the Belgrade–Niš railway in 1884. 

It was constructed in the Neo-Renaissance style, with a richly ornate façade, abounding in Neo-Classical elements and Neo-Baroque decoration. It was the first building to have a sous-terrain and elevated ground level with a garret roof.

As one of the most representative family houses of its time, it was used to entertain the Minister of Foreign Affairs of Imperial Russia, count Lamsdorf. During WWI when Niš was the war capital of Serbia, King Petar I Karađorđević lived in it. After WWII and the nationalization, its function was changed several times, until it finally became the building of Radio Niš in 1950.

In 1960, in order to meet the needs of Radio Niš, and according to the Niš architect Bora Spasić, another floor was added onto the ground level in the same style, giving the present-day appearance to the building.